Platelet rich plasma (PRP) is a simple, effective and minimally invasive method to naturally obtain a high concentration of autologous growth factors. The production of PRP, which contains a high concentration of platelets, involves centrifuging autologous blood to separate and remove the plasma and buffy coat portion of the whole blood. PRP offers usage in different fields such as dentistry, dermatology, plastic and maxillofacial surgery, acute trauma and plastic surgery. The main reason for the widespread use of PRP in the treatment of diseases with different pathophysiological mechanisms is that it contains important growth factors and other signaling molecules, including the presence of platelets and various blood cells, leukocyte-derived catabolic cytokines and fibrinogen, which can support and regulate the tissue repair process.

Platelet-rich fibrin (PRF); the structure, known as the second-generation platelet concentrate, is rich in autologous platelets and leukocytes that aim to accumulate platelets, immune modulators and inflammatory cytokines within the fibrin clot. Since the PRF preparation protocol is simple and effective and does not require any anticoagulant, the wound healing process due to the use of PRF is not prevented by anticoagulants and coagulation occurs naturally. PRF has several advantages, including a high concentration of leukocytes that not only play a role in immune and antibacterial responses but also support the wound healing process. PRF spontaneously forms a dense fibrin network, allowing the rate of degradation to slow down and thus delaying the release of growth factors into the surrounding tissue during wound healing.

It includes theoretical and practical training on PRP/PRF and PRP/PRF preparation and applications.