Considering the inadequacy of the methods used in the treatment of diseases today, there is a need to investigate effective treatment methods. In this context, cell and gene therapy will come to the fore as effective treatment methods in the future. Cellular and gene therapy is the transplantation of human cells or products produced by genetic engineering methods to replace or repair damaged tissues and/or cells. Innovative products produced with new generation technologies can be used in the treatment of many diseases and conditions or as part of the treatment. Some of the cellular and gene therapy products that can be used include hematopoietic stem cells, bone marrow-derived stem cells, mesenchymal stem cells, lymphocytes, dendritic cells and pancreatic islet cells, extracellular vesicles, exosomes and immunotherapeutic products.

Gene therapy aims to change or manipulate the expression of a gene or alter the biological properties of living cells for therapeutic use. Gene therapy is a technique that changes a person's genes to treat or cure disease. Gene therapies can work through a variety of mechanisms: replacing a disease-causing gene with a healthy copy, inactivating (silencing) a disease-causing gene that is not working properly, introducing a new or changed gene into the body to help treat a disease. Gene therapy products; It is being researched for the treatment of many diseases, especially cancer, genetic diseases and infectious diseases. Gene therapy products: Structures known as plasmid DNA contain circular DNA molecules and can be genetically engineered to deliver therapeutic genes into human cells. Viruses, while viral vectors, have a natural ability to transfer genetic material into cells, and therefore some gene therapy products are derived from viruses. Once viruses are modified to eliminate their ability to cause infectious diseases, these modified viruses can be used as vectors (vehicles) to deliver therapeutic genes into human cells. Bacterial vectors, on the other hand, can be modified to prevent them from causing infectious diseases and can then be used as vectors to deliver therapeutic genes into human tissues. Focusing on human gene editing technology, the aims of gene editing are to disrupt harmful genes or repair mutated genes. In patient-derived cellular gene therapy products, cells are taken from the patient, genetically modified (usually using a viral vector), and then returned to the patient.

Research and development activities include the discovery and production of cellular therapy and gene therapy products.